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The holidays aren't a holiday for everyone. We check in with people — from zookeepers to police officers — to hear what it's like to work on days when others are celebrating at home with loved ones.

The FDA approved the first gene-editing treatment for a human illness — the first genetic therapy for the brutal blood disorder sickle cell disease.

NPR's Scott Simon speaks to Heather Barr, Associate Director of the Women's Rights Division at Human Rights Watch, about a report showing how the Taliban takeover affected education in Afghanistan.

One of Edith Piaf's famous hits was "La Vie En Rose" but... how about "La Vie En AI"? A new biopic about the singer will be made using artificial intelligence to recreate her voice and image.

NPR's Scott Simon and ESPN's Michele Steele discuss the Shohei Ohtani sweepstakes, the NBA Cup Final and the Army-Navy game.

NPR's Scott Simon talks to former U.S. Ambassador to Ukraine, William Taylor, and war studies expert, Phillips O'Brien, about Ukraine. There's a stalemate on two fronts, the battlefield and funding.

NPR's Scott Simon speaks to Edward Geist, a policy researcher at the RAND Corporation, about his new book, "Deterrence under Uncertainty: Artificial Intelligence and Nuclear Warfare."

While the war in Gaza continues, tensions are rising in the West Bank where there are ongoing raids by the Israeli military and warnings of a possible uprising among Palestinians.

NPR's Scott Simon remembers television producer Norman Lear, who died this week at age 101.

Saleemul Huq influenced U.N. climate talks immensely over the years, by spotlighting what wealthy countries owe to less-developed nations. He died at 71, shortly before this year's COP28 talks began.